Searchable abstracts of presentations at key conferences in endocrinology

ea0060p03 | (1) | UKINETS2018

Second primary malignancies (SPMs) in patients with non-pulmonary well-differentiated neuroendocrine tumours (wdNETs)

Dafnis Anna , Raja Haseem , Chakrabarty Bipasha , Lamarca Angela , Hubner Richard A , Mansoor Wasat , Valle Juan W , McNamara Mairead

Background: Neuroendocrine tumours (NETs) are often associated with SPMs. This study aimed to identify SPMs in patients with non-pulmonary wdNETs.Methods: Patients seen at The Christie with non-pulmonary wdNETs from 2003–2017 were included. After exclusion of patients with hereditary predispositions, notes were retrospectively reviewed for location, functionality, treatment and temporal relation to diagnosis.Results: Of 854 pa...

ea0068p12 | Abstracts | UKINETS2019

Systemic chemotherapy for inoperable Goblet Cell Adenocarcinomas (GCAs)

Barriuso Jorge , Lamarca Angela , Martin Amy , Chakrabarty Bipasha , Clouston Hamish , Mullamitha Saifee , McNamara Mairead , Marti-Marti Francisca , Hubner Richard , Saunders Mark , O'Dwyer Sarah , Braun Michael , Valle Juan

Background: Appendiceal GCAs (previously known as Goblet Cell Carcinoids) are considered to have an unpredictable behaviour; even in node-negative patients, metastases mainly local to the adjacent peritoneum are seen. The systemic chemotherapy (scx) is often borrowed from colon cancer regimens. We designed a retrospective study with the aim of describing the use of scx in these rare malignancies in our institution.Methods: Data from all consecutive cases...

ea0052p19 | (1) | UKINETS2017

Mixed Adeno-Neuroendocrine Carcinoma (MANEC): a multicentre retrospective study

Frizziero Melissa , Wang Xin , Chakrabarty Bipasha , Childs Alexa , Luong Tu Vinh , Walter Thomas , Khan Mohid S. , Morgan Meleri , Christian Adam , Elshafie Mona , Shah Tahir , Fulford Paul , Minicozzi Annamaria , Mansoor Wasat , Meyer Tim , Hubner Richard A. , Valle Juan W. , McNamara Mairead G.

Introduction: MANEC is a rare diagnosis and little is known on its epidemiology/prognosis/management.Methods: Demographic/clinical-pathological/survival data of patients with a diagnosis of MANEC (2010 WHO criteria) from five European centres were retrospectively reviewed.Results: Sixty-six patients were identified (09/80–07/17); median age: 62.5 years (range 34–89); male: 66.7%; ECOG-PS 0-1: 59%; primary tumours from: sm...